Detalhe da pesquisa
1.
Cachexia: A systemic consequence of progressive, unresolved disease.
Cell
; 186(9): 1824-1845, 2023 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37116469
2.
GCN2 is required to maintain core body temperature in mice during acute cold.
Am J Physiol Endocrinol Metab
; 325(5): E624-E637, 2023 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37792040
3.
Activation and execution of the hepatic integrated stress response by dietary essential amino acid deprivation is amino acid specific.
FASEB J
; 36(7): e22396, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35690926
4.
Discordant regulation of eIF2 kinase GCN2 and mTORC1 during nutrient stress.
Nucleic Acids Res
; 49(10): 5726-5742, 2021 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34023907
5.
Biology of Activating Transcription Factor 4 (ATF4) and Its Role in Skeletal Muscle Atrophy.
J Nutr
; 152(4): 926-938, 2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34958390
6.
Physiologic Responses to Dietary Sulfur Amino Acid Restriction in Mice Are Influenced by Atf4 Status and Biological Sex.
J Nutr
; 151(4): 785-799, 2021 04 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33512502
7.
Metabolomics in equine sport and exercise.
J Anim Physiol Anim Nutr (Berl)
; 105(1): 140-148, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-32511844
8.
Age modulates liver responses to asparaginase-induced amino acid stress in mice.
J Biol Chem
; 294(38): 13864-13875, 2019 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31413113
9.
Mechanisms underlying reduced weight gain in intestinal fatty acid-binding protein (IFABP) null mice.
Am J Physiol Gastrointest Liver Physiol
; 318(3): G518-G530, 2020 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31905021
10.
Time-resolved analysis of amino acid stress identifies eIF2 phosphorylation as necessary to inhibit mTORC1 activity in liver.
J Biol Chem
; 293(14): 5005-5015, 2018 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29449374
11.
Obesity challenges the hepatoprotective function of the integrated stress response to asparaginase exposure in mice.
J Biol Chem
; 292(16): 6786-6798, 2017 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28242759
12.
Dietary Methionine Restriction Regulates Liver Protein Synthesis and Gene Expression Independently of Eukaryotic Initiation Factor 2 Phosphorylation in Mice.
J Nutr
; 147(6): 1031-1040, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28446632
13.
General control nonderepressible 2 deletion predisposes to asparaginase-associated pancreatitis in mice.
Am J Physiol Gastrointest Liver Physiol
; 310(11): G1061-70, 2016 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26968207
14.
The role of leucine and its metabolites in protein and energy metabolism.
Amino Acids
; 48(1): 41-51, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26255285
15.
GCN2 is required to increase fibroblast growth factor 21 and maintain hepatic triglyceride homeostasis during asparaginase treatment.
Am J Physiol Endocrinol Metab
; 308(4): E283-93, 2015 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25491724
16.
General control nonderepressible 2 (GCN2) kinase protects oligodendrocytes and white matter during branched-chain amino acid deficiency in mice.
J Biol Chem
; 288(43): 31250-60, 2013 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-24019515
17.
Off-target depletion of plasma tryptophan by allosteric inhibitors of BCKDK.
bioRxiv
; 2024 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38496495
18.
The eukaryotic initiation factor 2 kinase GCN2 protects against hepatotoxicity during asparaginase treatment.
Am J Physiol Endocrinol Metab
; 305(9): E1124-33, 2013 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24002574
19.
Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity.
Am J Physiol Endocrinol Metab
; 304(11): E1175-87, 2013 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23512805
20.
Detection of amino acid deprivation in the central nervous system.
Curr Opin Clin Nutr Metab Care
; 16(1): 96-101, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23222708